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Home > KRAS Pathway Inhibitors > Pan-KRAS Inhibitors > BI-2865

BI-2865

BI-2865 is a non-covalent pan-KRAS inhibitor, binding to KRAS WT, G12C, G12D, G12V, and G13D mutants with KD values of 6.9, 4.5, 32, 26, and 4.3 nM, respectively (ref 1).

Catalog NO:	CT-BI2865
Synonym:
CAS NO:	2937327-93-8
Mol. Formula:	C23H27N7O2S
MW:	465.6

** in vivo Quality Material. >99% Pure by Achiral and Chiral HPLCs (attached). Anhydrous, validated with a spot-on Elemental Analysis. Bulk stock. Same Day Shipping.

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	5 mg	$350.00	YES
2	10 mg	$450.00	YES
3	50 mg	$1,350.00	YES

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Solubility : Refer to Certificate of Analysis

Storage : Refer to Certificate of Analysis

Purity : >99% by Achiral and Chiral HPLCs

Original QC Data : Achiral and Chiral HPLCs, NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

BI-2865, Lot 01, Certificate of Analysis.pdf
BI-2865, Lot 01, Visual Appearance .pdf
C_K, BI2865, Lot 01, Achiral HPLC.pdf
C_K, BI2865, Lot 01, Chiral HPLC.pdf

1. Kim D, et al. Pan-KRAS inhibitor disables oncogenic signalling and tumour growth. Nature. 2023 Jul;619(7968):160-166.

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