AG014699 (Rucaparib) - Chemietek

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Home > Polymerase Inhibitor/Modulator > PARP (Poly (ADP-ribose) polymerase) > AG014699 (Rucaparib)

AG014699 (Rucaparib)

AG014699 (Rucaparib) is a selective PARP1 inhibitor (Ki = 1.4 nM) with potential antineoplastic activity. It selectively binds to PARP 1 and inhibits the PARP1-mediated DNA repair, thus potentiating the genomic instability and apoptosis.

Catalog NO:	CT-AG01
Synonym:	PF-01367338, Rucaparib
CAS NO:	459868-92-9
Mol. Formula:	C₁₉H₁₈FN₃O ∙ 0.2HCl
MW:	330.7

** An off-white to pale-yellow, recrystallized crystalline powder (see attached picture), clean (99.5% by HPLC) + impeccable NMR + an excellent quantitative elemental analysis. Bulk Stock!! Ship within 1 day.

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NO	Size	Price	In Stock	Quantity
1	5 mg	$100.00	YES
2	10 mg	$140.00	YES
3	50 mg	$280.00	YES
4	100 mg	$450.00	YES
5	200 mg	$750.00	YES

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Solubility : In DMSO, water with 1 eq of acid

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : 99.5% (HPLC)

Original QC Data : HPLC-MS, ¹HNMR, and Quantitative Elemental Analysis

Please Pick Batch NO:

Current Lot, Certificate of Analysis
Current Lot, NMR
Current Lot, HPLC-MS
AG014699 (Rucaparib), Lot 01 (current), Visual Appearance.pdf

1. Wang, Y. Frederick, Drugs of the Future (2009), 34(3), 177-182.

2. P. Plummer et al. Clin Cancer Res. 2008, 14(23), 7917-23

3. M. Ali et al. Clin. Cancer Res. 2009, 15(19), 6106-6112.

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