Uprosertib (GSK2141795) - Chemietek

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Home > Kinase Inhibitors > Akt/(PKB (Protein Kinase B) > Uprosertib (GSK2141795)

Uprosertib (GSK2141795)

Uprosertib (GSK2141795) is an orally bioavailable, selective and ATP-competitive pan-Akt (PKB) inhibitor, potently inhibiting Akt 1, 2, 3, and Akt 1 E17K mutation with IC50s of 0.066 nM, 2 nM, 1.4 nM, 1.5 nM, and 0.2nM, respectively.

Catalog NO:	CT-GSK214
Synonym:	GSK2141795, GSK795
CAS NO:	1047634-65-0 (free base) 1047635-80-2 (HCl salt)
Mol. Formula:	C₁₈H₁₆Cl₂F₂N₄O₂
MW:	429.2

** in vivo Quality material. 99.8-100% pure by achiral and chiral HPLCs (Attached). White crystalline powder, free base (Salt-free), validated by a spot-on quantitative microanalysis. Bulk stock!! Ship within 1 day.

Pricing and OrderingTechnical Data

QC & Certificates

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NO	Size	Price	In Stock	Quantity
1	5 mg	$90.00	YES
2	10 mg	$150.00	YES
3	50 mg	$420.00	YES
4	100 mg	$700.00	YES
5	200 mg	$1,250.00	YES

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Solubility : Soluble in DMSO

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : 99.5% chem purity (HPLC at 214 and 254 nm), 100% optical purity (Chiral HPLC), [α]²⁰_D = +5.4 ^o (c 1.0, MeOH)

Original QC Data : HPLC-MS, ¹HNMR, Chiral HPLC, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

Uprosertib, Current Lot, Certificate of Analysis
Uprosertib, Current Lot, NMR

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