PRODUCT

XL184 (free base) (Cabozantinib)  

Formula Image
Catalog Number:
CT-XL184
Synonym:
Cabozantinib
CAS Number:
1140909-48-3
Mol. Formula:
C26H24FN3O5
MW:
501.5

Technical Data:

Solubility: In DMSO
Storage: 0 °C (short term), -20 °C (long term), Desiccated
Purity: 99% chemical purity (HPLC at 214 and 254 nm)
Original QC
Data:
1HNMR and LC/MS
Shipping
Conditions:
Ambient Temp.

Price:

NO. Quantity Price In Stock
1 5 MG $100.00 YES
2 10 MG $140.00 YES
3 50 MG $400.00 YES
4 100 MG $600.00 YES
5 200 mg $950.00 YES

Please ask for quote for other quantities. White powder with clean QC data, Grams in stock from Indianapolis USA..

Brief Description:

XL184 is an orally active, multitargeted inhibitor of tumor growth, metastasis and angiogenesis, simultaneously targeting c-MET, RET and VEGFR2 with IC50s at low nM, currently in clinical trials.

References:

1. Kurzrock, R., et al., J Clin Oncol, 2011 Jul 1; 29(9): 2662-6. 2. Durante, C., et al., Expert Opin Investig Drugs, 2011 May; 20 (3): 403-413
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