PRODUCT

Ponatinib (HCl salt) (AP24534)  

Formula Image
Catalog Number:
CT-PONA
Synonym:
AP24534
CAS Number:
943319-70-8
Mol. Formula:
C29H27F3N6O∙ HCl
MW:
569.02

Technical Data:

Solubility: In DMSO and water
Storage: Store at 0°C (short term), -20°C (long term), desiccated
Purity: >99% chemical purity (HPLC)
Original QC
Data:
1HNMR, HPLC and MS
Shipping
Conditions:
Ambient Temp.

Price:

NO. Quantity Price In Stock
1 10 MG $55.00 YES
2 50 MG $90.00 YES
3 100 MG $145.00 YES
4 200 MG $210.00 YES
5 500 mg $380.00 YES

Please ask quote for other quantities. Grams in stock.

Brief Description:

Ponatinib is a potent, orally active and multi-targeted tyrosine kinase inhibitor for BCR-ABL, FGFRs, Flt-3, TIE2 and VEGFRs. Ponatinib is primarily used as an inhibitor of pan-BCR-ABL (and mutant forms) and pan-FGFR for treatment of hematological cancers.

References:

1. O’Hare, T., et al., Cancer Cell, 2009 Nov 6;16(5), 401-12. 2. Huang, WS., et al., J Med Chem. 2010 Jun 24;53(12), 4701-19.
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