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Pomalidomide
Pomalidomide, an analogue of thalidomide, is an immunomodulatory antineoplastic agent. Pomalidomide directly inhibits angiogenesis and myeloma cell growth. This dual effect is central to its activity in myeloma, rather than other pathways such as TNF alpha inhibition (ref. 1). It has also been report that Pomalidomide up regulates Interferon gamma, IL-2 and IL-10 as well as down regulates IL-6, which may contribute to its anti-angiogenic and anti-myeloma activities.
Catalog NO: CT-POMA
Synonym: CC-4047
CAS NO: 19171-19-8
Mol. Formula: C13H11N3O4· 0.2H2O
MW: 276.8
** in vivo grade material. 99.9% Pure by HPLC, coming with an impeccable 1H-NMR, and high-precision quantitative elemental analysis. Bulk stock, prompt.