LEE011 (Ribociclib) - Chemietek

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Home > Kinase Inhibitors > CDK (Cyclin-dependent Kinase) > LEE011 (Ribociclib)

LEE011 (Ribociclib)

LEE-011 is an orally bioavailable, potent and highly selective (most selective CDK4/6 inhibitor to date) cyclindependent kinase 4 and 6 (CDK 4/6) with IC50 at low nM, currently in clinical trials.

Catalog NO:	CT-LEE011
Synonym:	Ribociclib, LEE-011
CAS NO:	1211441-98-3
Mol. Formula:	C₂₃H₃₀N₈O∙
MW:	434.5 (or refer to Certificate of Analysis, batch-specific)

** in vivo Quality Material. >99% Pure, with Quantitative Elemental Analysis. Bulk. Same Day Shipping.

Pricing and OrderingTechnical Data

QC & Certificates

References

NO	Size	Price	In Stock	Quantity
1	10 mg	$70.00	YES
2	50 mg	$130.00	YES
3	100 mg	$210.00	YES
4	200 mg	$350.00	YES
5	500 mg	$595.00	YES

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Solubility : Soluble in DMSO, and water with 2.0 eq. of HCl

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99.5% (HPLC, detected at 214 and 254 nm)

Original QC Data : HPLC-MS, ¹HNMR, and Quantitative Elemental Analysis

Please Pick Batch NO:

LEE-011, lot 01, Certificate of Analysis.pdf
C_K, LEE-011, Lot 01, HPLC-MS.pdf
C_K, LEE-011, Lot 01, NMR.pdf

1. Rader J, et al. Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma. Clin Cancer Res. 2013 Oct 28.

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