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Home > Kinase Inhibitors > EGFR/HER2 > Lapatinib (free base)

Lapatinib (free base)

An epidermal growth factor (EGFR) and HER2/neu (ErbB-2) dual tyrosine kinase inhibitor.

Catalog NO:	CT-LP001
Synonym:	Tykerb
CAS NO:	231277-92-2
Mol. Formula:	C₂₉H₂₆ClFN₄O₄S
MW:	581.06

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NO	Size	Price	In Stock	Quantity
1	25 mg	$50.00	YES
2	100 mg	$100.00	YES
3	500 mg	$320.00	YES

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Solubility : Soluble in DMSO

Storage : Store at 0 °C (short term), -20 °C (long term), desiccated

Purity : > 99% (HPLC)

Original QC Data : ¹HNMR, HPLC

There is no COA file for this product

1. Chakrabarty A, Rexer BN, Wang SE, Cook RS, Engelman JA, Arteaga CL. H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation by heregulin production and activation of HER3. Oncogene. 2010 Jun 28. [Epub ahead of print] PubMed PMID: 20581867.

2. Nicoletta C, Lorenzo T, Anahi B, Raffaele P, Roberto M, Alberto B, Debora S, Eva M, Alessio N, Silvio P. Dynamic Simulations of Pathways Downstream of Erbb-Family, Including Mutations and Treatments. Concordance with Experimental Results. Curr Cancer Drug Targets. 2010 Jun 25. [Epub ahead of print] PubMed PMID: 20578981.

3. Becze E. Manage diarrhea and skin effects from lapatinib. ONS Connect. 2010 Jun;25(6):12-3.

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