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Home > Kinase Inhibitors > Bcr-Abl/c-kit/PDGFR/Src > Imatinib (free base)

Imatinib (free base)

A specific inhibitor of a number of tyrosine kinase (TK) enzymes, including the insulin receptor. Imatinib is specific for the TK domain in abl (the Abelson proto-oncogene), c-kit and platelet-derived growth factor receptor (PDGF-R).

Catalog NO:	CT-IM001
Synonym:	Gleevec
CAS NO:	152459-95-5
Mol. Formula:	C₂₉H₃₁N₇O
MW:	493.6

** Please ask for quote for other quantities. Grams in stock.

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NO	Size	Price	In Stock	Quantity
1	100 mg	$60.00	YES
2	500 mg	$120.00	YES
3	1 g	$180.00	YES

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Solubility : Soluble in DMSO

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : > 99% (HPLC)

Original QC Data : MS, ¹HNMR, HPLC

There is no COA file for this product

1. El-Deeb IM, Lee SH. Design and synthesis of new anticancer pyrimidines with multiple-kinase inhibitory effect. Bioorg Med Chem. 2010 Jun 1;18(11):3860-74.

2. Haouala A, Rumpold H, Untergasser G, Buclin T, Ris HB, Widmer N, Decosterd LA. siRNA-Mediated Knock-Down of P-Glycoprotein Expression Reveals Distinct Cellular Disposition of Anticancer Tyrosine Kinases Inhibitors. Drug Metab Lett. 2010 Apr 1;4(2):114-119.

3. Kodama Y, Kami M. [Economic burden for patients with chronic myelogenous leukemia--healthcare economics and medical governance of cancer]. Gan To Kagaku Ryoho. 2010 Apr;37(4):577-81. Review. Japanese.

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