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Home > Kinase Inhibitors > DNA-PK (DNA-Dependent Protein Kinase) > AZD7648

AZD7648

AZD-7648 is an orally available potent and selective next generation DNA-dependent protein kinase (DNA-PK) inhibitor (Enzymatic and Cellular IC50s = 0.6 nM, 91 nM, respectively ), highly selective against a panel of 397 other kinases, including closely-related Kinases such as ATM, ATR, and PI3Kα, β, δ, γ. Exhibits antitumor efficacy either as a monotherapy or in combination with either cytotoxic chemotherapies or novel Anti-Cancer agents.

Catalog NO:	CT-A7648
Synonym:	AZD-7648
CAS NO:	2230820-11-6
Mol. Formula:	C18H20N8O2
MW:	380.4

** in vivo Quality Material. 99.9% Pure by HPLC, clean and impeccable, coming with a spot-on high-precision Quantitative Microanalysis. Bulk stock! Prompt

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	10 mg	$120.00	YES
2	50 mg	$270.00	YES
3	100 mg	$450.00	YES
4	200 mg	$720.00	YES

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Solubility : Refer to Certificate of Analysis

Storage : Refer to Certificate of Analysis

Purity : >99.5% by HPLC (at 215 nm and 254 nm)

Original QC Data : HPLC-MS, NMR, and Quantitative Elemental Analysis Report

Please Pick Batch NO:

AZD7648, Lot 01, Certificate of Analysis.pdf
AZD7648, Lot 01, Visual Appearance.pdf

1. Fok JHL, et al, AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity, Nat Commun. 2019 Nov 7;10(1):5065.

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