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Skip Navigation LinksHome > Kinase Inhibitors > Akt/(PKB (Protein Kinase B) > Afuresertib (GSK2110183)
Afuresertib (GSK2110183)
Afuresertib (GSK2110183) is a cell-permeable, orally bioavailable, potent and selective ATP-competitive pan-AKT inhibitor with Ki at low nMs for all three iso-forms , currently in clinical evaluation for cancer treatment.
Catalog NO: CT-GSK211
Synonym: GSK2110183
CAS NO: 1047645-82-8 (HCl Salt) 1047644-62-1 (Free base)
Mol. Formula: C18H17Cl2FN4OS ∙ HCl
MW: 463.8
** A recrystallized white crystalline solid (see attached picture), clean (>99.5% by achiral HPLC), optically pure (100% ee by Chiral HPLC) + impeccable 1H-NMR, with a perfect Quantitative Elemental Analysis. Bulk in stock. Ship within 1 day.