Afuresertib (GSK2110183) - Chemietek

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Home > Kinase Inhibitors > Akt/(PKB (Protein Kinase B) > Afuresertib (GSK2110183)

Afuresertib (GSK2110183)

Afuresertib (GSK2110183) is a cell-permeable, orally bioavailable, potent and selective ATP-competitive pan-AKT inhibitor with Ki at low nMs for all three iso-forms , currently in clinical evaluation for cancer treatment.

Catalog NO:	CT-GSK211
Synonym:	GSK2110183
CAS NO:	1047645-82-8 (HCl Salt) 1047644-62-1 (Free base)
Mol. Formula:	C₁₈H₁₇Cl₂FN₄OS ∙ HCl
MW:	463.8

** in vivo grade material. 99.8-100% pure by achiral and chiral HPLCs. White crystalline powder, Mohohydrochloride (1xHCl Salt), validated by a spot-on quantitative microanalysis. Bulk stock!! Ship within 1 day.

Pricing and OrderingTechnical Data

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NO	Size	Price	In Stock	Quantity
1	5 mg	$80.00	YES
2	10 mg	$120.00	YES
3	50 mg	$300.00	YES
4	100 mg	$450.00	YES
5	200 mg	$790.00	YES

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Solubility : Soluble in DMSO and Water

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : 100% optical purity (chiral HPLC), >99.5% chemical purity (achiral HPLC at 214 and 254 nm)

Original QC Data : HPLC-MS, ¹HNMR, Chiral HPLC, and Quantitative Elemental Analysis

Please Pick Batch NO:

Afuresertib, Current Lot, Certificate of Analysis
Afuresertib, Current Lot (01), Appearance (color).pdf

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