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Home > Polymerase Inhibitor/Modulator > PARP (Poly (ADP-ribose) polymerase) > ABT-888 (Veliparib)

ABT-888 (Veliparib)

ABT-888 is a potent and orally active poly(ADP-ribose) polymerase (PARP) inhibitor with Ki at low nM (< 5nM in vitro). It does not inhibit other NAD-binding enzymes.

Catalog NO:	CT-A888
Synonym:	Veliparib
CAS NO:	912444-00-9
Mol. Formula:	C₁₃H₁₆N₄O ∙ 2HCl
MW:	317.21

** Grams in stock from Indianapolis USA. A dihydrochloride salt*, optically pure (100% ee), with clean analytical data + Quantitative Elemental Analysis. Ship within 1 day.

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NO	Size	Price	In Stock	Quantity
1	10 mg	$95.00	YES
2	50 mg	$250.00	YES
3	100 mg	$400.00	YES

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Solubility : Soluble in DMSO, Water

Storage : Store at 0°C (short term), -20°C (long term), desiccated

Purity : >99.5% chem and optical purity (HPLC, Chiral HPLC)

Original QC Data : HPLC-MS, ¹HNMR, Chiral HPLC, and Quantitative Elemental Analysis

Please Pick Batch NO:

ABT-888, Current Lot, COA
ABT-888, Current Lot, NMR
ABT-888, Current Lot, HPLC and Chiral HPLC

1. Albert, J.M., et al, Inhibition of poly(ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models, Clin. Cancer Res. 13, 3033 (2007).

2. Donawho, C.K. et al.; ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models, Clin. Cancer Res. 13, 2728 (2007)

*Confirmed by Quantitative Elemental Analysis

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